TY - JOUR AU - Oluah, Ndubuisi S. AU - Chineke, Agatha C. PY - 2014/03/01 Y2 - 2024/03/29 TI - Alterations in the Biochemical Parameters of the African Catfish Clarias Gariepinus [Burchell] Exposed to Sublethal Concentrations of Lambda-Cyhalothrin JF - Annals of Environmental Science JA - AES VL - 8 IS - 0 SE - Articles DO - UR - https://openjournals.library.northeastern.edu/aes/journal/article/view/v8art1 SP - AB - <p>Pesticide contamination of water bodies is increasingly becoming a threat to aquatic life with its attendant public health implications. With this in mind, this study was undertaken with a view to evaluating the effect of chronic exposure to λ-cyhalothrin on some biochemical parameters (cholesterol, glycogen, glucose and protein) in the freshwater catfish <em>Clarias gariepinus</em>. The fingerlings were exposed to sublethal concentrations (0.0, 0.01 and 0.04 mg/L) of λ-cyhalothrin for 21 days in a static renewal bioassay system. The LC<sub>50</sub> value determined by probit analysis was 0.103 mg/L. The cholesterol concentration was significantly higher (P &lt; 0.05) in the treatment groups when compared with the control. The increase was both concentration and duration-dependent. The protein concentration in the λ-cyhalothrin-exposed fish was significantly lower than the control (p &lt; 0.05) except on day 7, when the serum protein level did not differ from the group exposed to 0.01 mg/L λ-cyhalothrin. Similarly, when compared with the control, the liver glycogen and serum glucose concentrations decreased significantly (p &lt; 0.05) with increasing λ-cyhalothrin test concentration and duration of exposure. The observed hypercholesterolemia with concomitant hypoglycemia and hypoprotenemia are indications of stress due to λ-cyhalothrin exposure.</p><p>&nbsp;</p><p><strong>Permanent URL: </strong><a href="http://hdl.handle.net/2047/d20004933">http://hdl.handle.net/2047/d20004933</a></p> ER -